Deep Caries in Mature Teeth With Reversible Pulpitis

Launched by MINIA UNIVERSITY · Jun 11, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how the dental pulp—the soft tissue inside your tooth—responds when treating deep cavities in mature adult teeth that have a mild, reversible inflammation called reversible pulpitis. The researchers want to compare two ways of removing the decayed parts of the tooth to see which method better preserves the health of the pulp. They will look at the results through clinical exams, X-rays, and by examining the tooth tissue under a microscope after extraction.

Adults between 18 and 40 years old who have a deep cavity affecting a back tooth, but still have a healthy pulp that reacts to cold tests and no signs of severe infection, might be eligible. Teeth must be fixable with a simple filling and free from serious gum disease or other complications. Participants can expect to have their decayed tissue removed using one of two methods, followed by a direct filling, with careful monitoring of the tooth’s health. This study is not yet recruiting, but it aims to help dentists better understand how to treat deep cavities while keeping the tooth’s nerve healthy.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. The patient's age from 18 years to 40 years old
• • 2. Non -contributory medical history (ASA1)
• • 3. Mature permanent posterior teeth with primary or secondary deep caries extending ≥ 2/3 of dentin
• • 4. The tooth should give a positive response to cold testing
• • 5. Clinical diagnosis of reversible pulpitis
• • 6. The tooth is restorable via direct restoration, probing pocket depth and mobility are within normal limits
• • 7. No signs of pulpal necrosis including sinus tract or swelling
• • 8. No radiographic evidence of periapical changes indicative of apical periodontitis
• Exclusion Criteria:
• • Systemic medical conditions, pregnancy, alcoholic and smoker patients. 2- Teeth with spontaneous pain or percussion sensitivity in periodontal lesions, external or internal root resorption, sinus opening, mobility, or abscessed tooth. 3- Radiographic evidence of widened periodontal space, broken or interrupted lamina dura, and periapical radiolucency. 4- Intensified erosion damage or periodontitis. Patient reported clenching or bruxism, hopeless or non-restorable teeth. Immature teeth. 5- Patients with physical disabilities preventing tooth brushing. Patient had removable partial denture abutments, dental abscesses, pulp lesions, atypical facial pain, or pulpitis. 6- Patients had non-carious lesions like abrasion, erosion, attrition, or abfraction.
• • 7- Patients with history of antibiotic or analgesics intake within few days of operative intervention. 8- Patients with previously root canal-treated teeth. 9- Periodontally compromised teeth. 10-Teeth that will be extracted for periodontal or orthodontic reasons as it will conduct for histological evaluation