HIV/HBV/HCV Triple Screening in Primary Care

Launched by UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER · Jun 12, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at the best way for primary care doctors to screen their adult patients for three important viruses that affect the blood: HIV, hepatitis B (HBV), and hepatitis C (HCV). The study will compare two approaches: one where doctors order tests as they normally do, and another where a special “triple test” panel automatically includes screening for all three viruses whenever a doctor orders a test for any one of them. The goal is to see if using this triple test helps find more cases of these infections early, how it affects costs, and how often patients are tested.

Doctors who provide care to adults in outpatient settings and plan to continue their practice for at least a year can take part in the study. Those who agree will be randomly assigned to either use the usual testing method or the triple test panel for six months, then switch to the other method for another six months. Doctors will still have control over which tests get ordered before finalizing them. This study will help understand if screening for all three viruses together might improve early diagnosis and care for patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Outpatient primary care adult providers at participating institutions
• • Providers who provide consent to participate in this study.
• • Providers must intend to continue their current practice for at least 12 months.
• Exclusion Criteria:
• • Providers who do not consent to participate
• • Sub-specialty providers
• • Pediatric providers
• • Providers who anticipate leaving their current practice within the next 12 months (i.e. providers who plan to retire, move, etc.).
• • Note: family medicine and med/peds providers can participate, but only for their adult patients. The intervention order panel and any data collection will be restricted to adult patients ≥ 18 years old.