Electroacupuncture Combined With Immune Checkpoint Inhibitors as Adjuvant Therapy After Surgery for Early-stage Non-small Cell Lung Cancer
Launched by KONG FANMING · Jun 15, 2025
Trial Information
Current as of August 25, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying whether adding electroacupuncture (a therapy where small electrical currents are applied through acupuncture needles) to a type of cancer treatment called immune checkpoint inhibitors can help people who have had surgery for early-stage non-small cell lung cancer (NSCLC). The goal is to see if this combined approach can lower the chances of the cancer coming back, improve the effects of the immune treatment, and help patients live longer with a better quality of life.
People who might be eligible for this study are adults between 18 and 80 years old who have had surgery for stage II or IIIA/B NSCLC, have already received some chemotherapy after surgery, and do not have certain genetic mutations in their cancer. They should be in generally good health, able to take care of themselves, and willing to follow the study plan. Participants can expect to receive regular treatments including electroacupuncture alongside their standard immune therapy, and doctors will closely monitor their health and cancer progress. This study is important because it looks at combining traditional Chinese medicine with modern cancer treatments to find new ways to improve recovery and survival after lung cancer surgery.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • (1) Non-tumor patients with stage Ⅱ, ⅢA, ⅢB (N2) non-small cell lung cancer diagnosed by pathology or cytology after surgery; (2) driver mutations negative patients; (3) Postoperative adjuvant chemotherapy was received for 1 to 4 cycles;(4)conforms to two qi syndrome of traditional Chinese medicine syndrome differentiation diagnosis of patients; (5) aged 18 to 80 years old; (6) expected lifetime \> 6 months; (7) ECOG 0 to 2 points; (8) patients willing to accept this solution treatment, adherence to the good.
- Exclusion Criteria:
- • (1) Patients with other malignant tumors in the past or at the same time within 5 years; (2) has a serious heart, liver and kidney damage, or other serious complications; (3) the R1, R2, need after resection, postoperative adjuvant radiotherapy patients; (4) with mental disorders; (5) has a variety of drug allergy, allergic constitution; (6) in pregnancy or lactation women.
About Kong Fanming
Kong Fanming is a dedicated clinical trial sponsor committed to advancing medical research through innovative and rigorous study designs. With a focus on enhancing patient outcomes, Kong Fanming collaborates with leading healthcare professionals and institutions to facilitate the development of novel therapies across various therapeutic areas. The organization prioritizes ethical standards and regulatory compliance, ensuring that all trials are conducted with the highest level of integrity and transparency. Through its commitment to scientific excellence and patient-centric approaches, Kong Fanming aims to contribute significantly to the advancement of healthcare and the improvement of global health outcomes.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Tianjin, , China
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported