Functional Outcomes in Ulcerative Colitis Patients With Ileal Pouch Anal Anastomosis Treated With High Intensity Focused Electromagnetic Stimulation
Launched by CEDARS-SINAI MEDICAL CENTER · Jun 19, 2025
Trial Information
Current as of June 26, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how well a treatment called High Intensity Focused Electromagnetic Stimulation (using a device called the Emsella chair) works to improve bowel control and quality of life in people who have ulcerative colitis or a similar condition and have had a surgery called a J pouch (ileal pouch anal anastomosis). This surgery creates a new way for stool to leave the body after the colon is removed. The study will look at how this treatment affects fecal incontinence, which means trouble controlling bowel movements, before, during, and after treatment.
People who might be eligible for this study are adults 18 years or older who have had a J pouch surgery at least one year ago because of ulcerative colitis or indeterminate colitis and currently experience fecal incontinence. Participants should not have active infections or complications in the pouch, other serious bowel conditions, implanted metal or medical devices, or be pregnant. If you join the study, you can expect to receive treatment with the Emsella chair and have your symptoms and quality of life monitored throughout the process. This trial is not yet recruiting, but it aims to help people with bowel control problems after J pouch surgery find new ways to feel better.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Individuals 18 years old or older are included.
- • Patients who have a J pouch reconstruction due to Ulcerative Colitis or IBDU
- • Must be at least 1 year out from J pouch surgery
- • Have fecal incontinence
- Exclusion Criteria:
- • Any records flagged "break the glass" or "research opt out."
- • Pediatric Patients \<18 years of age
- • Did not receive a J pouch
- • Patients who received a J pouch for any other indication, including but not limited to Crohn's disease, familial adenosis polyposis
- • Have active pouchitis
- • Have an active fistula
- • If reclassified to de novo Crohn's after surgery
- • Have implanted metal devices or medical devices
- • Pregnant patients
About Cedars Sinai Medical Center
Cedars-Sinai Medical Center is a renowned nonprofit academic medical center located in Los Angeles, California, recognized for its commitment to patient care, research, and education. As a leading institution in clinical trials, Cedars-Sinai harnesses innovative approaches to advance medical knowledge and improve treatment outcomes across various specialties. With a multidisciplinary team of experts, state-of-the-art facilities, and a patient-centered approach, Cedars-Sinai actively contributes to the development of novel therapies and interventions, ensuring the highest standards of clinical research while prioritizing patient safety and ethical considerations.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Los Angeles, California, United States
Patients applied
Trial Officials
Karen Zaghiyan, MD
Principal Investigator
Cedar Sinai Medical Center
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported