Temporary Aortic Compression With the Abdominal Tourniquet for Refractory Postpartum Hemorrhage

Launched by LLC UKRMEDGROUP · Jun 15, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new medical device called the Abdominal Aortic and Junctional Tourniquet - Stabilized (AAJT-S) to help control severe bleeding after childbirth, specifically when usual treatments don’t work. This bleeding, known as postpartum hemorrhage, can happen when the uterus doesn’t contract properly, causing heavy blood loss. The study aims to see if using this device temporarily to compress a major blood vessel in the abdomen is safe, practical, and effective in stopping the bleeding.

Women who might be eligible for this study are those 18 years or older who have heavy bleeding after delivery that hasn’t improved with standard treatments like medications or a balloon placed inside the uterus to stop bleeding. The bleeding must be quite severe—more than about 1.3 liters of blood lost. Women whose bleeding is caused by injury, retained placenta, or blood clotting problems won’t be included. Participants will be asked to give their informed consent before the device is used. If accepted into the trial, they can expect the device to be applied temporarily to help control bleeding while doctors manage the situation. This study is not yet recruiting participants.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Age ≥18 years
• • Clinical diagnosis of postpartum hemorrhage (PPH) refractory to uterotonics and intrauterine balloon tamponade
• • Estimated blood loss greater than 1300 mL
• • Oral informed consent provided prior to device application
• Exclusion Criteria:
• • Patients with postpartum bleeding as a result of trauma, retained placenta or coagulopathy were excluded