Isokinetic Strength Training On Functional Performance
Launched by KAFRELSHEIKH UNIVERSITY · Jun 16, 2025
Trial Information
Current as of July 25, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at how a special type of strength training, called isokinetic strength training, can help boys with hemophilia improve the function of their knees. Hemophilia is a condition where the blood does not clot properly, which can cause bleeding inside joints and muscles, leading to pain and muscle loss. The study focuses on boys who have moderate hemophilia and experience bleeding and pain in one knee but are still able to stand and walk on their own.
If selected, participants will be asked to take part in training that uses machines designed to safely measure and improve muscle strength by controlling the speed of movement. The trial aims to see if this training can help strengthen muscles around the knee, reduce symptoms, and improve how well the knee works. Boys eligible for the study are between 9 and 15 years old, have no serious joint damage or other health problems, and are medically stable. This study is not yet open for recruitment, but it offers a promising way to help children with hemophilia stay active and maintain muscle strength safely.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- * Patients of both groups (study and control groups ) were selected according to the following criteria:
- • 1. Each group contained 15 male children. They were suffering from unilateral knee heamarthrothesis .
- • 2. The joint problems (pain and bleeding ) ranges from mild to moderate according to the classification of hemophilia recommended by the Orthopedic advisory committee of the World Federation of hemophilia (appendix 1) (Holder and Cotta, 1989).
- • 3. Patients were able to stand and walk independently.
- • 4. They had no neurological or psychological problems.
- • 5. All patients were clinically and medically stable.
- • 6. They were able to understand the requirements of the study.
- • 7. They were suffering from moderate hemophilia.
- • 8. They were not suffering from acute joint and muscle bleeds during treatment time.
- • 9. None of the children suffered from fixed deformities of the affected lower limb.
- • 10. All the children received the same medical treatment to control bleeding.
- • 11. They had no visual no hearing deficits B. Exclusion criteria
- • <!-- -->
- 1. Patients with advanced radiographic changes including:
- • Bone destruction.
- • Bony ankylosis .
- • Knee joint subluxation.
- • Epiphyseal fracture.
- • 2. Patients who had congenital or acquired skeletal deformities in both lower limbs.
- • 3. Patients who had any neurological deficits such as convulsions involuntary movements or those receiving muscle relaxants.
- Exclusion Criteria:
About Kafrelsheikh University
Kafrelsheikh University, a prominent academic institution located in Egypt, is dedicated to advancing medical research and clinical trials that contribute to the enhancement of healthcare practices and patient outcomes. With a strong emphasis on interdisciplinary collaboration, the university harnesses its diverse expertise in medical sciences, engineering, and technology to conduct rigorous clinical studies. Kafrelsheikh University aims to foster innovation in clinical research, ensuring compliance with ethical standards and regulatory requirements, while actively engaging in community health initiatives to address pressing health challenges. Through its commitment to excellence, the university seeks to develop evidence-based solutions that improve health and well-being at both local and global levels.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported