Application of Low-dose Muscle Relaxants in Bronchoscopic Interventional Procedures

Launched by HARBIN MEDICAL UNIVERSITY · Jun 15, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how using a small dose of muscle relaxants during bronchoscopy—a procedure that looks inside the lungs—affects patients compared to not using these relaxants. Researchers want to see if the muscle relaxants make it easier and safer to insert the breathing tube after anesthesia, reduce spasms in the throat, lessen coughing and movement during the procedure, and help patients recover better afterward.

The study is open to adults aged 18 and older who are having planned bronchoscopic surgery lasting at least 20 minutes and are generally healthy enough for anesthesia. People with certain health issues, like severe heart or kidney problems, very high weight, or a history of breathing or anesthesia difficulties, cannot join. Participants will be divided into two groups: one will receive a low dose of muscle relaxants during anesthesia, and the other will not. The team will then observe how well each method works and how safe it is. If you or a family member are preparing for this type of lung procedure and meet the criteria, this study might be an option to discuss with your doctor.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients undergoing elective electronic bronchoscopic interventional surgery;
• • 2. Age 18 years or older;
• • 3. American Society of Anesthesiologists (ASA) I-III;
• • 4. The duration of bronchoscopic surgery \>=20min;
• • 5. Through pre-anesthesia assessment, the patient/family member has informed consent and signed the consent form;
• • 6. The general clinical information of the patient is complete.
• Exclusion Criteria:
• • 1. Patients with predictable difficult airway;
• • 2. Small mouth opening (\<2 transverse fingers);
• • 3. Combined with severe cardiovascular disease, abnormal liver and kidney function;
• • 4. Morbidly obese patients with body mass index (BMI) greater than 35kg/m\^2;
• • 5. Has a history of gastroesophageal reflux disease.
• • 6. High risk of reflux aspiration;
• • 7. Those who have a history of abnormal surgical anesthesia recovery in the past;
• • 8. Patients with mental illness and previous allergies to conventional anesthetic drugs.