Transmission of Oncogenic HPV Infection Among Families

Launched by TAMPERE UNIVERSITY HOSPITAL · Jun 16, 2025

Keywords

ClinConnect Summary

This study is looking at how certain types of human papillomavirus (HPV) that can lead to cancers—like cervical cancer and some head and neck cancers—are passed between family members. Researchers want to learn more about how HPV spreads between sexual partners and from parents to their children. They will also explore how other microbes (tiny organisms like bacteria) might affect how long HPV infections last and how likely they are to cause cancer.

The study will include up to 300 couples from clinics in Finland, along with their children who are over 12 years old. Eligible participants are people who have a long-lasting HPV infection, cervical cancer, or HPV-related head and neck cancer, as well as their partners and children. Those taking part will provide samples from their mouth and private areas themselves, several times over up to five years. They will also fill out questionnaires about their health, habits, and environment. The information gathered will help improve HPV screening and prevention, and may identify new signs that increase cancer risk. This study is not yet enrolling participants, and you need to speak Finnish to take part.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patient with colposcopy clinic detected persisting HR-HPV infection
• • Patient with diagnosed cervical cancer
• • Patient with diagnosed OSCC
• • Patients' sexual partners of women or men that are referred to the colposcopy/gynecological oncology/ENT
• • offspring (over 12 years old) of the referred couples
• Exclusion Criteria:
• • Candidate who don't speak Finnish