Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF)

Launched by SANOFI · Jun 25, 2025

Keywords

ClinConnect Summary

This study is focused on finding early signs of Type 1 Diabetes (T1D) in children and teenagers who have a close family member, like a parent or sibling, with T1D. The goal is to detect the condition before symptoms appear, so doctors can better monitor and manage the risk. The study will follow international guidelines to make sure the screening and data collected are done in a consistent and reliable way.

Children and teens between 1.5 and 18 years old who have a parent, brother, or sister with Type 1 Diabetes may be eligible to join. If you decide to participate, there will be two visits over about 13 months. The first visit is for initial screening, and the second visit is to confirm the results. It’s important to note that children who already have diabetes or have been treated with insulin won’t be able to participate. Parents or legal guardians will need to give permission for their child to take part. This study is not yet open for enrollment, but it aims to help catch Type 1 Diabetes early in those most at risk.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Children and adolescents, age 1.5 years to 18 years
• • First degree relatives of T1D probands
• • Parent or legal guardian signing an informed consent
• Exclusion Criteria:
• • Already developed clinical overt T1D
• • Known diabetes of any kind (type 1, type 2, Maturity Onset Diabetes of the Young - MODY)
• • Have a previous history of being treated with insulin