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Search / Trial NCT07038616

Observation of the Response to Ovulation Triggering on the Day of Intrauterine Insemination and Correlation Between Progesterone Level and Pregnancy Rate (OVUL-IIU)

Launched by CENTRE HOSPITALIER INTERCOMMUNAL CRETEIL · Jun 17, 2025

Trial Information

Current as of July 24, 2025

Recruiting

Keywords

Stimulated Cycle Intrauterine Insemination Clinical Pregnancy Rate Donor Sperm Progesterone Ovulation Induction Ovulation

ClinConnect Summary

This clinical trial is studying how the timing of ovulation triggering (using medication to help the ovary release an egg) on the day of intrauterine insemination (IUI) affects pregnancy rates. IUI is a common fertility treatment where sperm is placed directly into the uterus to help a woman conceive. The study aims to see if there is a connection between the levels of a hormone called progesterone (which supports pregnancy) on the day of insemination and the chances of becoming pregnant.

Women aged 18 to 43 who are undergoing IUI, whether single or in a couple (including same-sex couples), may be eligible to join. As part of the study, participants will have routine blood tests on the day of insemination to measure certain hormone levels. The goal is to better understand how these hormone levels relate to successful pregnancies after IUI, which could help improve timing and treatment in the future. Participation involves usual care with some extra blood tests, and all information will be collected with the patient’s consent.

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • Single women or couples, heterosexual or homosexual, undergoing insemination at the medically assisted procreation.center
  • Aged 18 to 43
  • Any indication for IUI in compliance with the Recommendations for Good Practices in MPA (RBP)
  • Blood test on the day of insemination with estradiol, progesterone, LH and hCG measured as part of routine care
  • Exclusion Criteria:
  • -Opposition of patients to data collection

About Centre Hospitalier Intercommunal Creteil

Centre Hospitalier Intercommunal Créteil (CHIC) is a leading healthcare institution in the Val-de-Marne department of France, dedicated to delivering high-quality medical care and advancing clinical research. As a prominent clinical trial sponsor, CHIC collaborates with healthcare professionals and academic institutions to facilitate innovative research initiatives aimed at improving patient outcomes. The center is committed to adhering to rigorous ethical standards and regulatory guidelines, ensuring the safety and efficacy of interventions tested within its clinical trials. CHIC’s multidisciplinary approach fosters an environment of collaboration and excellence, positioning it as a key player in the advancement of medical knowledge and therapeutic options.

Locations

Creteil, , France

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported