Clinical Alternatives for Reducing Harm Using E-cigarettes

Launched by MEDICAL UNIVERSITY OF SOUTH CAROLINA · Jun 18, 2025

Keywords

ClinConnect Summary

This clinical trial is studying whether switching completely from regular cigarettes to e-cigarettes can help people with cancer who smoke but do not want to use traditional quitting methods. Quitting smoking is very important for patients in cancer care, but many refuse treatments like counseling or medication. This study will look at using e-cigarettes as a safer alternative to reduce harm from smoking in these patients.

To take part, you must be at least 21 years old, currently smoking, and have declined all usual quitting treatments offered through a hospital program. You also need to speak English and not have used e-cigarettes or other quitting aids recently. Pregnant women and people in prison cannot join. If you participate, you will be asked to switch completely from cigarettes to e-cigarettes, and researchers will follow your progress to see if this helps reduce harm. The study is not yet recruiting but will include about 208 patients receiving cancer care.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • age 21+,
• • identified as smoking in their medical record and self-report of current smoking within the past 30 days
• • refused traditional treatment options through the opt-out HCC Tobacco Treatment Program
• • English speaking;
• Exclusion Criteria:
• • currently taking part in any TTP or using cessation medication (i.e., taking NRT or other cessation medications, enrolled in the Quitline, or in another study),
• • use of e-cigarettes in the past 30 days,
• • currently imprisoned,
• • pregnant women.