Gustabor Phase 1 - AI-based Creation of a Nutritional Plan to Compensate for Chemotherapy-induced Taste Disorders

Launched by WUERZBURG UNIVERSITY HOSPITAL · Jun 17, 2025

Keywords

ClinConnect Summary

This clinical trial is exploring a new way to help people who have taste changes caused by cancer treatments, such as chemotherapy. These taste problems can make eating difficult and sometimes lead to poor nutrition or stopping treatment. The study will use a computer program (artificial intelligence, or AI) to create personalized meal plans based on each person’s specific taste changes. The goal is to find foods that taste better and are easier to enjoy during treatment, helping patients maintain good nutrition.

People who might join this study are adults with certain types of cancer, including multiple myeloma or cancers of the digestive system, who mainly eat by mouth and are experiencing taste changes related to their cancer treatment. Participants will need to be able to use an online portal and prepare or have help preparing the suggested meals. The study will follow them over about 12 weeks to see if the personalized meal plans are helpful. This trial is not yet recruiting, and it’s important to note that people who are pregnant, have taste changes from other causes, or live in inpatient care facilities are not eligible.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 18
• • Suffering from one of the following tumor entities: Multiple myeloma or malignant tumor of the gastrointestinal tract
• • Mainly oral nutrition
• • Subjectively perceived tumor therapy-related taste disorder
• • At least two clinical presentations planned within 12 weeks with a minimum interval of three weeks
• • Ability to participate in nutritional intervention, including use of the online portal and implementation of recipe suggestions (e.g. resources and access to a kitchen), either independently or with third-party support (e.g. by relatives, outpatient care services).
• Exclusion Criteria:
• • Pregnancy
• • Taste disorder explained by other causes (e.g. existing before therapy or COVID disease)
• • Placement in an inpatient care facility