Microvascular Profiling of Nodules in the Thyroid Gland
Launched by RIGSHOSPITALET, DENMARK · Jun 19, 2025
Trial Information
Current as of September 10, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is studying tiny blood vessels in lumps (called nodules) that can form in the thyroid gland, which is a small organ in your neck that helps control your metabolism. Using a special type of ultrasound, the researchers want to learn more about these blood vessels to help doctors better tell the difference between harmless and potentially harmful nodules. This could eventually help decide who needs surgery and who might not.
People over 18 years old with different types of thyroid nodules, including those who have been told they might have cancer in their thyroid, may be able to join. Healthy volunteers without thyroid problems are also welcome. Participants will undergo an advanced ultrasound exam of their thyroid nodules. The study is not yet recruiting, so if you’re interested, you’ll need to wait until it opens. It’s important to note that pregnant women and those who cannot have the ultrasound for physical or mental reasons cannot join. Participants will be asked to give consent and may learn important health information discovered during the study.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age over 18 years
- • Written and verbal informed consent to participate in the study
- • Patients with hypo-, iso-, or hyperfunctioning thyroid nodules
- • Patients referred for thyroid surgery due to suspected malignant nodule (including Bethesda classification groups III, IV, V, and VI)
- • Healthy volunteers - generally good health with no chronic illnesses
- Exclusion Criteria:
- • Pregnancy
- • Inability to undergo the examination due to physical or mental limitations
- • Desire to opt out of receiving information about new, significant health findings revealed during the study
- * Healthy Participants:
- • Thyroid disease, including nodules, as well as current or past conditions affecting the thyroid
- • Medication that affects thyroid function
About Rigshospitalet, Denmark
Rigshospitalet, located in Copenhagen, Denmark, is one of the leading hospitals in Scandinavia and a prominent center for clinical research and innovation. As a key academic institution affiliated with the University of Copenhagen, Rigshospitalet is dedicated to advancing healthcare through rigorous clinical trials and groundbreaking research across various medical disciplines. The hospital’s commitment to excellence is reflected in its multidisciplinary approach, collaboration with international research networks, and focus on improving patient outcomes through evidence-based practices. With state-of-the-art facilities and a team of highly qualified professionals, Rigshospitalet plays a crucial role in translating scientific discoveries into effective treatments and therapies.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Copenhagen, Denmark
Lyngby, Denmark
Patients applied
Trial Officials
Michael Bachmann Nielsen, Professor PhD dr.med.
Principal Investigator
Rigshospitalet, Denmark
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported