Effects of Rebonding Technique and Final Cure in Post-operative Hypersensitivity in Class 1 Composite Restorations
Launched by FOUNDATION UNIVERSITY ISLAMABAD · Jun 19, 2025
Trial Information
Current as of October 02, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
This study is looking at ways to prevent post‑operative tooth sensitivity after a common back‑tooth filling (class 1 composite restoration). Researchers are comparing four groups: two using a total‑etch bonding agent (with and without a rebonding step) and two using a self‑etch bonding agent (with and without rebonding). Rebonding is a technique thought to seal gaps left by the filling process. The main question is whether rebonding and/or the type of bonding agent can reduce sensitivity after treatment, measured right away and again about one week later on a 0–10 pain scale (0 = no pain, 1–3 mild, 4–6 moderate, 10 = worst).
Who can join? Adults 18 and older with a class 1 cavity in a premolar or molar that reaches the middle third of dentin, and signs of reversible pulpitis (short, sharp pain to hot/cold or sweet stimuli). People are excluded if they have widespread tooth sensitivity, a cavity near the tooth nerve, cavities needing pulp capping, poor oral hygiene or gum disease, bruxism, or certain medications. The trial is being conducted at Foundation University Islamabad in Pakistan, aims to enroll about 120 people, and is currently enrolling by invitation. It started in May 2025 and is expected to finish around October 2025; results aren’t available yet.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • class 1 carious lesion in premolar and molars clinically diagnosed as moderate occlusal caries extending up to middle third of dentin no caries on any other surface of tooth patients with sign and symptom of reversible pulpitis like sharp pain, sensitivity to hot and cold and sweet stimuli lasting foe few seconds
- Exclusion Criteria:
- • history of generalized sensitivity cavities extending up to pulpal third of dentin cavities need to be restored with direct or indirect pulp capping poor oral hygiene or periodontal disease bruxism and other wear facets chronic anti inflammatory, analgesics or psychotropic drugs
About Foundation University Islamabad
Foundation University Islamabad (FUI) is a prominent educational institution dedicated to advancing research and innovation in various fields, including clinical sciences. With a commitment to excellence in education and healthcare, FUI fosters a collaborative environment that encourages multidisciplinary research initiatives. The university actively engages in clinical trials aimed at improving patient outcomes and contributing valuable insights to the medical community. Through its state-of-the-art facilities and a team of experienced professionals, Foundation University Islamabad strives to uphold the highest ethical standards in clinical research, ensuring the integrity and reliability of its findings.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Islamabad, Federal, Pakistan
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported