Effects of Total and Selective Caries Removal - Requiring or Avoiding Vital Pulp Therapy - on Pulp Vitality and Postoperative Pain in Deep Carious Mature Permanent Teeth: A Split-Mouth Clinical Study

Launched by CUKUROVA UNIVERSITY · Jun 19, 2025

Keywords

ClinConnect Summary

This clinical trial is studying two different ways of cleaning deep tooth decay to see how they affect the health of the tooth’s nerve (called the pulp) and any pain after treatment. One method removes all the decay, while the other removes only some of it to avoid exposing the nerve. The goal is to find out which approach better keeps the nerve healthy and reduces pain after the procedure.

People who might take part are teenagers and adults (15 years and older) who have deep decay in matching teeth on both sides of their mouth, and whose tooth nerves are still alive and sensitive to cold, but who do not have ongoing pain or serious infection around the tooth roots. Participants should also be willing to return for check-ups after 6 and 12 months. If you join, you can expect the dentist to use both cleaning methods on different teeth in your mouth, and then monitor how your teeth feel and heal over time. This study is not yet recruiting, and it excludes those with certain health issues, pregnant women, or teeth that are too damaged to fix.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients aged ≥15 years with bilateral deep carious mature permanent teeth.
• • Positive vitality test (cold sensitivity).
• • No spontaneous pain or periapical radiolucency.
• • Willingness to attend 6- and 12-month follow-ups
• Exclusion Criteria:
• • Uncontrolled systemic diseases Pregnancy or allergy to dental materials used Teeth with irreversible pulpitis (spontaneous pain, necrosis) Non-restorable teeth (fractures, extensive decay)