The Influence of Virtual Reality on Blood Parameters

Launched by VAN CREVELDKLINIEK · Jun 19, 2025

Keywords

ClinConnect Summary

This study is looking at how virtual reality (VR) experiences might affect certain stress-related substances in the blood. Healthy adults will watch two types of VR videos: one that is relaxing and another that is designed to be stressful, like a rollercoaster ride. The researchers will take blood samples before and after each VR experience to see if these videos cause any changes in stress levels in the body.

To join this study, participants need to be between 18 and 45 years old and able to give written consent. People with certain health conditions, such as blood or hormone disorders, heart problems, epilepsy, or those who are pregnant, cannot take part. During the study, participants will visit twice, about 3 to 5 weeks apart, watching one type of VR video each time for about five minutes, with blood samples taken before and after. This research might help us understand how VR can influence stress and the body’s response to it.

Gender

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Eligibility criteria

• Inclusion Criteria:
• • Age between 18 and 45 years old;
• • Willing and able to provide written informed consent.
• Exclusion Criteria:
• • A history of motion- or cybersickness;
• • Fear of needles;
• * Any of the following haematological disorders:
• • Congenital or acquired haemophilia A;
• • Von Willebrand Disease.
• * Any of the following endocrinological disorders:
• • Thyroid disorders (e.g. hypo/hyperthyroidism);
• • Cushing syndrome;
• • Adrenal insufficiency;
• • Diabetes mellitus type 1 or 2;
• • Central or nephrogenic AVP deficiency.
• • A confirmed cardiac disorder;
• • All types of epilepsy;
• • Every form of medication, except for intermittent use of pain killers but not in the last week (e.g. paracetamol) and an intra-uterine device with or without contraceptive;
• • Pregnancy.