H-Reflex Suppression by Bone Myoregulation Reflex During Mechanical Loading in Standing Humans

Launched by ISTANBUL PHYSICAL MEDICINE REHABILITATION TRAINING AND RESEARCH HOSPITAL · Jun 27, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how standing and gentle vibrations affect a natural reflex in the leg called the H-reflex, which helps control muscle activity and balance. Researchers want to learn more about how the nervous system and bones work together to keep us steady and moving well while standing. To do this, they will measure electrical signals in a calf muscle of healthy adults as they stand still or experience mild vibration.

The study is looking for healthy adults between 20 and 45 years old who can stand on their own for at least 10 minutes and do not have any problems with their nerves, muscles, or balance. Participants will be asked to stand quietly or with gentle whole-body vibrations while special sensors record muscle responses. This is a non-invasive test, meaning no surgery or injections are involved. If you meet the criteria and are interested, this study aims to help us understand balance and movement better, which could one day improve treatments for people with related health issues.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Healthy adults aged 20 to 45 years
• • Able to stand independently for at least 10 minutes
• • No known neurological, orthopedic, or balance disorders
• • Willingness to participate and provide informed consent
• Exclusion Criteria:
• • History of spinal cord injury, peripheral neuropathy, or muscle disease
• • Recent lower limb surgery or musculoskeletal trauma
• • Current use of medications affecting neuromuscular function
• • Pregnancy
• • Any contraindications to exposure to mechanical vibration