A Cataract Surgery Clinical Trial

Launched by ALCON RESEARCH · Jun 24, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at two different systems used during cataract surgery to see which one works better and is safer for patients. Cataracts happen when the lens in your eye becomes cloudy, making it hard to see. The study compares the UNITY™ Vitreoretinal Cataract System and the CENTURION® Vision System with Active Sentry, both used to remove cataracts in adults with a moderate level of lens cloudiness in both eyes.

To join the study, participants need to be between 65 and 74 years old and have a similar level of cataracts in both eyes, meaning the cloudiness should be about the same in each eye. Both eyes also need to be suitable for the same type of lens implant and the same supportive eye gel used during surgery. People who are planning other eye surgeries, like glaucoma surgery, or have other eye conditions that could affect the study are not eligible. Participants will have about eight visits over the course of a month, during which their vision and eye health will be checked to see how well each system works and how safe it is. This study is not yet recruiting, but it aims to help improve cataract surgery options in the future.

Gender

ALL

Eligibility criteria

• Key Inclusion Criteria:
• • Clinically documented diagnosis of age-related nuclear sclerotic cataract of grade 2 or greater in both eyes;
• • Both eyes with similar nuclear sclerotic cataract severity and type (within 1 cataract grade);
• • Both eyes able to be implanted with same intraocular lens material;
• • Both eyes able to receive the same ophthalmic viscosurgical device (OVD).
• • Other protocol-specified inclusion criteria may apply.
• Key Exclusion Criteria:
• • Planned intraoperative glaucoma surgery or expected postoperative procedures during the study in either study eye;
• • Laser-assisted cataract surgery in either study eye;
• • Any ocular disease and/or condition that, in the investigator's clinical judgement, may put the subject at significant risk, may compromise study results, or may interfere significantly with the subject's participation in the study.
• • Other protocol-specified exclusion criteria may apply.