Betadine vs Sterile Water for Periurethral Preparation

Launched by UNIVERSITY OF LOUISVILLE · Jun 25, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at the best way to clean the area around the urethra—the opening where urine leaves the body—before placing a temporary catheter, which is a small tube used to drain urine from the bladder. The study compares two cleaning methods: sterile water (water that’s been cleaned to remove germs) and Betadine (a common medical cleaning solution). Researchers want to see if one method leads to fewer bacteria in the urine afterward and whether one causes less discomfort or pain during the catheter placement.

Women aged 18 and older who need a catheter placed in a doctor’s office might be eligible to join, as long as they don’t have certain health issues like frequent urinary infections, recent catheter use, iodine allergies, or pregnancy in the later stages. Participants will have their urethra cleaned with either sterile water or Betadine before the catheter is put in, and the study will monitor bacteria levels in the urine and any discomfort experienced. This research could help improve how catheters are placed and make the process more comfortable and safer for patients.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Aged 18+
• • Patient undergoing in office straight catherization
• Exclusion Criteria:
• • History of culture proven recurrent urinary tract infection (2 in any 6-month period or 3 in any 12-month period)
• • Urine Analysis with +Nitrites
• • Catherization for any reason in the last 4 weeks
• • History of Iodine allergy
• • Patients unable to speak English
• • Patient does not have the capacity to consent
• • 2-3rd trimester pregnancy