Improving Personalized Treatment in Oncology: Effects of Integrated Oncological Decision-making
Launched by LEIDEN UNIVERSITY MEDICAL CENTER · Jun 23, 2025
Trial Information
Current as of July 22, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a new way to help doctors and patients make cancer treatment decisions together. The approach, called the Integrated Oncological Decision-making Model (IODM), looks at medical options, the patient’s overall health, and what the patient wants from their treatment. The goal is to see if this personalized method leads to treatment choices that better fit each patient’s needs and improve their outcomes compared to standard care based only on medical guidelines.
Adults aged 18 and older who are starting cancer treatment at one of four medical centers in the Netherlands may be eligible to join, as long as they can understand Dutch and participate in making decisions about their care. About 400 patients will take part. Some will receive usual care, while others will use the new IODM approach. Participants can expect to be involved in discussions about their treatment options, share their health status and personal goals, and complete questionnaires about their experience. This study aims to better tailor cancer treatments to individual patients, making the decision process more personalized and meaningful.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patient's age = 18+
- • Patient is included in participating oncological care path
- • Patient does not yet have a treatment plan
- • Patient, partner, or caregiver who reads and speaks Dutch sufficiently to understand the research material and to complete the questionnaires
- • Patient must be able to participate in the decision-making process
- Exclusion Criteria:
- • • Patient, partner, or caregiver cannot give informed consent
About Leiden University Medical Center
Leiden University Medical Center (LUMC) is a prominent academic medical center located in the Netherlands, renowned for its commitment to advancing healthcare through innovative research and high-quality patient care. As a clinical trial sponsor, LUMC focuses on translating scientific discoveries into effective therapies, fostering collaborations between researchers, clinicians, and industry partners. The center is dedicated to conducting rigorous clinical studies across various medical fields, ensuring adherence to ethical standards and regulatory requirements while prioritizing patient safety and outcomes. Through its multidisciplinary approach, LUMC aims to contribute significantly to the understanding and treatment of complex health conditions, driving progress in personalized medicine and improving global health.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Maastricht, , Netherlands
Groningen, , Netherlands
Leiden, , Netherlands
Sittard, , Netherlands
Patients applied
Trial Officials
Lieke Welling, MD PhD (Dr)
Principal Investigator
Department of Surgery
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported