Efficacy of Dietary Interventions and Educational Programs as Adjunctive Therapies for the Management of Urolithiasis: Efficacy of Fresh Lemon Juice and Roselle as Educational Program on Urolithiasis Parameters

Launched by HAWLER MEDICAL UNIVERSITY · Jul 1, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at whether drinking fresh lemon juice or hibiscus tea (also known as Roselle), combined with an educational program, can help manage kidney stones. Kidney stones are hard mineral deposits that form in the urinary tract and can cause pain, infections, and other problems. The study aims to see if these natural drinks, along with learning more about lifestyle changes, can reduce stone size, symptoms, and complications better than education alone or no treatment.

Adults between 18 and 75 years old who have been diagnosed with kidney stones may be eligible to join, as long as they aren’t already using lemon juice, Roselle, or similar herbal treatments. People with certain health issues like severe kidney disease, allergies to these plants, recent surgery for stones, or other serious illnesses won’t be included to keep the study safe and reliable. Participants will be divided into groups to receive either lemon juice plus education, Roselle tea plus education, education only, or no intervention, and their progress will be closely monitored. This study hopes to find simple, natural ways to help prevent kidney stones from coming back and improve patients’ quality of life.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * The following aspects is considered for the inclusion of participants in the study:
• • Adults aged 18-75 years diagnosed with urolithiasis.
• • Patients are willing to participate and provide informed consent.
• • Patients do not currently use lemon juice, Roselle, or other herbal treatments for urolithiasis.
• • No history of severe gastrointestinal disorders or metabolic conditions interfering with dietary interventions.
• Exclusion Criteria:
• * Based on predefined criteria, patients are excluded if they have:
• • Allergies to citrus fruits or hibiscus.
• • Chronic kidney disease (CKD) stage 3 or higher.
• • Pregnancy or lactation.
• • Gastrointestinal disorders (e.g., GERD, ulcers, chronic gastritis for lemon juice group).
• • Metabolic disorders (e.g., hyperparathyroidism, gout, hyperoxaluria).
• • Recent urolithiasis surgery (within the last 3-6 months).
• • Severe systemic diseases (e.g., cancer, advanced cardiovascular diseases).
• • Hypertension requires diuretics (due to potential interaction (synergic effect) between dietary interactions and prescribed medications for hypertension which may lead to hypotension).
• • Malabsorption disorders (e.g., Crohn's disease, celiac disease).
• • Non-compliance with study protocols. The exclusion criteria ensure homogeneity in the study sample and improve the reliability of intervention assessment.