Sarcoma Surgery Wound Complications Comparing Usual Versus Negative Pressure Dressing
Launched by NHS GREATER GLASGOW AND CLYDE · Jun 24, 2025
Trial Information
Current as of July 24, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial, called SUNDIAL, is looking at how different types of wound dressings affect healing after surgery to remove sarcoma, which is a type of cancer that can occur in the arms, legs, or torso. The study is comparing the usual absorbent dressings, which soak up fluids from the wound, with a newer method called Negative Pressure Wound Therapy (NPWT). NPWT uses a special dressing connected to a gentle vacuum to help the wound heal. The researchers want to see which dressing leads to fewer complications and better overall outcomes, including costs and recovery.
People who might take part are adults aged 16 and older who have sarcoma in their limbs or torso and are scheduled for surgery to remove the tumor. To join, participants need to be able to give informed permission and follow the study visits and procedures. The trial excludes those who have had previous surgery in the same area, have widespread cancer seen on scans, or are allergic to adhesive dressings. If someone joins, they can expect to receive one of the two dressing types after their surgery and be monitored to see how well their wound heals and if any problems occur. This study is not yet recruiting, but it aims to help improve care for people recovering from sarcoma surgery.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Sarcoma of the upper/lower limb or torso requiring wide local excision, planned marginal excision or amputation
- • Able to provide informed consent
- • Aged 16 years or over
- • Able, and willing, to adhere to scheduled trial procedures and visit schedule
- Exclusion Criteria:
- • Previous surgery to planned surgical field
- • Contra-indication to surgical excision of the tumour
- • Disseminated malignancy on pre-op radiological imaging
- • Post-radiation sarcoma
- • Allergy to adhesive dressing
- • Subjects who, in the opinion of the PI, will be unable to comply with follow-up
About Nhs Greater Glasgow And Clyde
NHS Greater Glasgow and Clyde (NHS GG&C) is one of the largest health organizations in the UK, dedicated to delivering high-quality healthcare services to a diverse population. As a clinical trial sponsor, NHS GG&C plays a pivotal role in advancing medical research and improving patient outcomes through innovative clinical studies. The organization is committed to upholding rigorous ethical standards and regulatory compliance, ensuring that all trials are conducted with the utmost care for participant safety and scientific integrity. With a focus on collaboration, NHS GG&C partners with academic institutions, healthcare professionals, and industry stakeholders to foster an environment conducive to groundbreaking research and the development of new therapies.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Glasgow, Scotland, United Kingdom
Patients applied
Trial Officials
Sanjay Gupta, MBBS, MRCS, MSc, MPhil, FRCS
Principal Investigator
Department of Trauma and Orthopaedics, Glagow Royal Infirmary, NHS Greater Glasgow and Clyde
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported