Cohort Study of Intrauterine Diseases

Launched by WENWEN WANG · Jun 24, 2025

Keywords

ClinConnect Summary

This clinical trial is studying diseases that affect the inside of the uterus, such as endometrial cancer, thickening of the uterine lining (called endometrial hyperplasia), and growths known as endometrial polyps. The goal is to better understand what causes these conditions, identify risk factors, and find the best ways to treat them. To do this, the study will gather detailed information about each participant’s medical history, menstrual and pregnancy history, physical exams, imaging tests, lab results, and tissue samples taken during a procedure called hysteroscopy (a camera exam inside the uterus). After this procedure, participants will be followed for one year to monitor how their condition changes over time.

Women between the ages of 18 and 80 who need a hysteroscopy or a similar diagnostic procedure for uterine issues may be eligible to join the study. Participants will need to agree to the follow-up visits and give informed consent, meaning they understand the study and agree to take part. People who are already in other drug trials or who cannot safely have the hysteroscopy procedure won’t be able to join. If you decide to participate, you can expect a thorough evaluation and regular check-ins over the course of a year to track your health and help researchers learn more about these uterine conditions.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Age: 18-80 years;
• • Patients requiring hysteroscopy or diagnostic curettage for intrauterine pathologies (e.g., endometrial hyperplasia, endometrial polyps, submucosal uterine fibroids, adenomyosis, or endometrial malignancies);
• • Willing and able to comply with follow-up requirements;
• • Signed informed consent obtained.
• Exclusion Criteria:
• • Concurrent participation in other drug clinical trials;
• • Contraindications to or inability to tolerate hysteroscopy/curettage procedures;
• • Unwilling or unable to provide informed consent;
• • Unwilling or unable to adhere to study protocols.