Anxiolytic Effect of Virtual Reality Immersion Versus Midazolam Premedication in Patients Undergoing Dacryocystorhinostomy Surgery

Launched by CAIRO UNIVERSITY · Jun 25, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at ways to help reduce anxiety in adults who are having a specific eye surgery called Dacryocystorhinostomy (DCR), which is done under general anesthesia. The study compares two methods: using virtual reality (VR) to help patients relax before surgery, and giving a common anti-anxiety medicine called Midazolam. The goal is to see which method works better to keep patients calm and stable during the procedure.

Adults aged 18 to 65 who are generally healthy and scheduled for DCR surgery may be able to join the study. People with heart or kidney problems, certain mental health conditions, or those who feel uncomfortable with VR or have issues like severe eye irritation won’t be eligible. If you join, you’ll either wear a VR headset to help distract and relax you before surgery or receive the usual medication. The researchers will then monitor how well each method helps reduce anxiety and keeps your vital signs steady. This study aims to find a comfortable and safe way to ease patients’ worries before surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Aged 18-65.
• • Both sexes.
• • American Society of Anesthesiologists (ASA) classification: I - II.
• • Patient undergoing Dacryocystorhinostomy Surgery (DCR) operation under general anesthesia.
• Exclusion Criteria:
• • Patient refusal.
• • Patients with cardiac diseases.
• • Patients with renal diseases.
• • Patients with drug sensitivity and seizures.
• • Substance abuse and addiction.
• • Claustrophobia.
• • Patients with cerebrovascular disease.
• • Psychiatric and cognitive disorder.
• • Patients with severe teary eyes and blurring of vision.
• • Patients who express discomfort during the test.