Effect of Neurodynamic Moblization Versus Mulligan on Pain and Functional Abilities in Patients With Chronic Discogenic Sciatica
Launched by CAIRO UNIVERSITY · Jun 25, 2025
Trial Information
Current as of July 22, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is studying two different types of physical therapy techniques—called neurodynamic mobilization and Mulligan SNAG’s mobilization—to see which one is better at reducing pain and improving movement in people who have chronic sciatica caused by a specific type of disc problem in the lower back. Sciatica is a condition where pain travels along the sciatic nerve, usually causing discomfort in one leg. The goal is to find out which treatment helps people feel better and move more easily.
To join the study, participants need to be between 35 and 50 years old, have had sciatica for at least six months caused by a bulging disc in the lower spine (confirmed by MRI and physical exams), and have pain on just one side of their body that follows the path of the sciatic nerve. People with other back problems, recent injuries, infections, or who have had back surgery won’t be eligible. If accepted, participants will receive one of the two therapies, and the researchers will measure how their pain and ability to move change over time. This study is not yet recruiting participants but aims to help find better ways to manage long-lasting sciatica pain.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • All the patients diagnosed as lumbar radiculopathy (L5-S1) for at least six months. Diagnosis was confirmed by physical, neurological examination (motor assessment, sensory assessment, reflexes) and radiological assessment (CT or MRI).
- • All patients has second grade of disc bulge which will detect from T2 axial view of MRI according to Fardon and Milette
- • All patients has unilateral radiculopathy and pain in the distribution of scaitic nerve.
- • The age of the patients will range from 35 to 50years . Their body mass index will range between( 22-25)
- Exclusion Criteria:
- • Bilateral and multilevel disc prolapse or bilateral radtadiating pain
- • acute pain (pain less than three months).
- • Presence of active infection in lumbar spine.
- • Any other spinal deformities.
- • Postoperative cases.
- • Cauda equine lesion.
- • Neoplasmic.
- • Spinal stenosis.
- • Mechanical low back pain.
- • Failed back syndrome.
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported