The Influences of Blood Flow Restriction on Leg Press

Launched by SALISBURY UNIVERSITY · Jun 26, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how using special blood flow restriction cuffs during leg press exercises affects things like blood vessel stiffness, muscle size and strength, exercise performance, and how participants feel about the experience. Blood flow restriction cuffs are bands placed on the legs to gently reduce blood flow during exercise, which may help improve muscle growth and strength.

To take part, you need to be physically active for at least six months and have maintained a stable weight during that time. The study is looking for adults of all genders between the ages of about 65 and 146 (this appears to be a typo, likely meaning 65 to 74). People with certain health conditions, such as high blood pressure, diabetes, serious heart or lung diseases, or those who are pregnant, are not eligible. If you join, you will use different types of these cuffs while doing leg press exercises, and researchers will monitor how your body responds and how you feel. The study has not started recruiting yet, but it aims to better understand how these cuffs might help improve muscle health safely during exercise.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Physically active (\> 1,000 MET/min/wk) for at least six months.
• • 2. Weight stable for previous 6 months (+/-2.5 kg)
• Exclusion Criteria:
• • 1. Stage 2 hypertension (SBP \>/= 140 and/or DBP \>/= 90 mmHg)
• • 2. BMI\>40 kg/m2
• • 3. Diabetes
• • 4. Familial hypercholesterolemia
• • 5. Past or current history of CHD, stroke or major CVD events. Respiratory diseases (not including asthma), endocrine or metabolic, neurological, or hematological disorders that would compromise the study or the health of the subject.
• • 6. Participants must not be pregnant, plan to become pregnant during the study, or be nursing
• • 7. Active renal or liver disease
• • 8. All medications and supplements that influence dependent variables\*
• • 9. Recent surgery \< 2 months
• • 10. Alcohol abuse
• • 11. Sleep apnea