Effect of Different Drugs on Emergency Delirium in Preschool Age Patient
Launched by ZAGAZIG UNIVERSITY · Jul 6, 2025
Trial Information
Current as of July 27, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at how different medicines might help prevent a condition called emergence delirium in young children aged 3 to 5 years old after eye muscle surgery (called squint surgery) performed under general anesthesia with a gas called sevoflurane. Emergence delirium is when a child wakes up from anesthesia feeling confused, upset, or restless, sometimes crying or moving around a lot, which can be distressing for both the child and their parents. The study aims to find out which medicine works best to reduce these symptoms and make recovery more comfortable and safer.
Children eligible to take part are those between 3 and 5 years old, in good general health, and scheduled for squint surgery using sevoflurane anesthesia. Parents or close family members must agree to participate. Children who are very anxious before surgery, have behavioral or neurological conditions, or are taking sedative medicines regularly will not be included. If your child joins the trial, they will receive one of the study medicines during surgery, and doctors and nurses will carefully watch how they wake up and recover to see if the medicine helps prevent emergence delirium. This study is not yet recruiting participants but aims to improve care and comfort for children undergoing surgery.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Parents or first degree relative acceptance. - Age: 3-5 years old. - Body weight: 5% -85% of BMI (kg /m2) of the same age and sex. - Sex: Both sexes. - Physical Status: Of class I and II according to American Society of Anesthesiologists (ASA) classification. - Type of surgery: Squint surgeries under sevoflurane anesthesia.
- Exclusion Criteria:
- • - Children with score 3 (i.e. anxious and crying) according to the three-point anxiety scale (Kain et al. 2004). - Children with preexisting abnormal behavior, psychiatric disorders, developmental delay or central nervous system diseases (epilepsy). - Children with chronic use of sedative drugs. - Children with severe respira
About Zagazig University
Zagazig University, a prominent educational and research institution located in Egypt, plays a pivotal role in advancing medical knowledge and promoting health innovations through its clinical trials. With a commitment to excellence in research, the university leverages its diverse expertise and state-of-the-art facilities to conduct rigorous clinical studies that aim to improve patient care and outcomes. By fostering collaboration among multidisciplinary teams, Zagazig University contributes significantly to the global medical community, ensuring that its clinical trials adhere to the highest ethical standards and regulatory requirements.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported