Residual Stenosis and Restenosis Following Carotid Endarterectomy With Primary Closure, A Prospective Tracking Study

Launched by CHARLES UNIVERSITY, CZECH REPUBLIC · Jun 30, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how often and when narrowing of the carotid artery (a main artery in the neck that supplies blood to the brain) happens or returns after a common surgery called carotid endarterectomy (CEA). This surgery is done to remove blockages and help prevent strokes. The study will follow patients who have this surgery using a specific method called primary closure, to see how well it works over time and if any narrowing remains or comes back within a year after surgery.

People who might join this study are adults between 18 and 90 years old who are having elective carotid endarterectomy and do not have certain health issues like previous similar surgeries, high surgical risk, or specific nerve problems in the neck. Participants will have scans before surgery, then again about one month and one year after, to check their artery’s condition. The study will also watch for any complications like stroke or heart problems. This research is being done in several centers in the Czech Republic, using the same surgery and testing methods, to provide clear information on how safe and effective this surgery technique is in the long run.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients without matching any of exclusion criteria who underwent cartotid endarterectomy
• Exclusion Criteria:
• • Age ≤18 or ≥90 years
• • Previous endarterectomy or stenting
• • Unsuitable vascular anatomy
• • High perioperative risk
• • Contralateral cranial nerve X or XII palsy
• • History of neck irradiation
• • Tandem carotid stenosis or intracranial vascular pathology (e.g., aneurysm or AVM)
• • Absence of signed informed consent