The Effect of Pulsed Electromagnetic Field Therapy on Muscle Mass and Muscle Strength in Prostate Cancer Patients Treated With Androgen Deprivation Therapy

Launched by CHINESE UNIVERSITY OF HONG KONG · Jul 4, 2025

Keywords

ClinConnect Summary

This clinical trial is studying whether a treatment called Pulsed Electromagnetic Field Therapy (PEMF) can help improve muscle size and strength in men with prostate cancer who are receiving a common hormone therapy known as Androgen Deprivation Therapy (ADT). ADT can sometimes cause muscle loss and weakness, so this study aims to see if PEMF can counteract these effects and help patients feel stronger.

Men who might join the study are those diagnosed with prostate cancer that hasn’t spread to other parts of the body, who have been on hormone therapy for between six months and three years, and plan to continue this treatment for at least six more months. Participants should be able to walk at least 400 meters and have completed any recent prostate surgery or radiation therapy at least four weeks ago. During the study, participants will receive the PEMF treatment, and researchers will check their muscle mass and strength to see if there’s improvement. This trial is currently recruiting men aged 65 to 74, and it’s important for those interested to meet the criteria to ensure the treatment can be safely and effectively tested.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Adult patients with age greater than or equal to 18 years old.
• • Histologically documented PCa
• • No evidence of distant metastasis (M1 disease)
• • With ADT exposure from six months to three years
• • Expected to continue for at least six months
• • At least four weeks after radical prostatectomy or completed radiotherapy
• Exclusion Criteria:
• • Patients are still under active treatment, such as radiotherapy
• • Patients who are unable to walk for 400 m or undertake exercise that will affect the clinical assessment of muscle strength
• • Patients with amputated lower limbs or other body deformities that will affect the treatment protocol