Tubeless VATS for Lung Cancer Surgery

Launched by THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIVERSITY · Jun 30, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new way to perform lung cancer surgery called “tubeless video-assisted thoracic surgery” (or tubeless VATS). This approach avoids using a breathing tube during surgery, which may reduce the amount of anesthesia needed, cause less injury to the lungs, help patients recover faster, and even lower carbon emissions to support environmentally friendly medical care. The study will compare this tubeless method with the traditional surgery that uses a breathing tube to see which is safer and better for patients over the long term.

Patients who are 18 years or older and scheduled for planned lung cancer surgery using VATS may be eligible to join. To participate, patients need to have a type and stage of lung cancer that can be treated with surgery, be healthy enough for this kind of procedure, and be willing to follow up with doctors after surgery for tests and check-ups. People who have severe heart or lung problems, need emergency surgery, or have other health issues that make this surgery unsafe won’t be able to join. If you take part, you can expect to be closely monitored before, during, and after surgery to see how well you recover and how the new tubeless technique compares to the usual method.

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Eligibility criteria

• Inclusion Criteria:
• • 1. Patients aged ≥18 years scheduled for elective video-assisted thoracic surgery (VATS) for confirmed or suspected lung cancer.
• • 2. Clinical stage suitable for surgical resection (lobectomy, segmentectomy, or wedge resection).
• • 3. American Society of Anesthesiologists (ASA) physical status classification ≤III.
• • 4. Ability to understand and willingness to provide written informed consent.
• • 5. Agreement to adhere to scheduled postoperative clinical follow-up assessments, including pulmonary function tests and survival status evaluations.
• Exclusion Criteria:
• • 1. Patients requiring bilateral pulmonary procedures or planned open thoracotomy.
• • 2. History of severe cardiopulmonary disease or unstable medical conditions that contraindicate minimally invasive thoracic surgery.
• • 3. Emergency surgery due to acute respiratory or cardiovascular instability.
• • 4. Inability to cooperate with the planned anesthetic and surgical protocols or postoperative follow-up procedures.
• • 5. Pregnancy or lactation at the time of enrollment.
• • 6. Known allergy or contraindication to anesthetic agents or materials used in the study.
• • 7. Enrollment in another interventional clinical study within the past 30 days.