Meaning-centered Intervention for Internalizing Symptoms
Launched by UNIVERSITY OF GRONINGEN · Jul 4, 2025
Trial Information
Current as of September 25, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
This study is testing whether a six-session online program designed to help people find meaning in life can reduce depressive and anxious symptoms in young adults. Participants are first-year psychology students at the University of Groningen who have higher levels of internalizing symptoms. They are randomly assigned to either the meaning-centered program or a waitlist (no immediate program). The researchers will compare changes in meaning in life and internalizing symptoms right after the program and again about one month later.
Eligibility includes adults 18 or older with elevated depressive/anxiety symptoms (PHQ-4 score of 2 or higher) who are not currently in psychotherapy and have no suicidality. The program consists of six 1-hour online sessions led by a trainer (about every four days) with optional homework, available in English, Dutch, or German. If you’re in the waitlist group, you’ll begin the program after the study period. Participants complete surveys at baseline, after the intervention (or after four weeks for waitlist), and at a one-month follow-up, measuring meaning in life and symptom levels, with some additional questions about related factors. This trial is currently enrolling, with about 142 participants planned, and results are not yet available.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • heightened internalizing symptoms (depressive and/or anxiety symptoms) as indicated by PHQ-4 total score of 2 or higher
- Exclusion Criteria:
- • receiving psychotherapeutic treatment for a depressive or anxiety disorder
- • suicidality
About University Of Groningen
The University of Groningen, a prestigious research institution located in the Netherlands, is dedicated to advancing medical knowledge through innovative clinical trials. Renowned for its commitment to academic excellence and interdisciplinary collaboration, the university leverages its extensive expertise in various fields, including medicine, health sciences, and biomedical research, to foster groundbreaking studies. By engaging in rigorous scientific inquiry and adhering to ethical research practices, the University of Groningen aims to contribute significantly to the development of new treatments and therapies, ultimately enhancing patient care and public health outcomes.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Groningen, Netherlands
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported