Effect of Pre- and Postoperative ESP Block on Frontal QRS-T Angle in Laparoscopic Cholecystectomy

Launched by HARRAN UNIVERSITY · Jul 9, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how a type of pain relief called the Erector Spinae Plane (ESP) block, given either before or after surgery, affects the heart's electrical activity in people having a laparoscopic gallbladder removal. The heart’s electrical activity will be measured using a test called an electrocardiogram (ECG) before surgery and one hour after. Researchers want to see if the timing of this pain relief method influences a specific heart measurement that can show how stable the heart’s rhythm is during the recovery period.

Adults aged 18 to 65 who are generally healthy and scheduled for elective laparoscopic gallbladder surgery may be eligible to join. To participate, patients need to have a normal heart rhythm before surgery and must give informed consent. If you join the study, you will be randomly placed into one of three groups: no ESP block, ESP block before surgery, or ESP block after surgery. You will have ECG tests before and after the procedure to monitor any changes. This study aims to help doctors understand the safest way to use this pain relief technique to protect the heart during surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age between 18-65 years
• • ASA physical status I-II
• • Scheduled for elective laparoscopic cholecystectomy
• • Voluntary written informed consent obtained
• • Normal preoperative 12-lead ECG (no conduction abnormalities or arrhythmias)
• Exclusion Criteria:
• • History of cardiac disease (e.g., arrhythmia, myocardial infarction, heart failure)
• • Current use of medications affecting cardiac conduction (e.g., antiarrhythmics, beta-blockers)
• • Known allergy to local anesthetics
• • Coagulation disorders or current anticoagulant therapy
• • Pregnancy or breastfeeding
• • Local infection or anatomical deformity at the ESP block injection site
• • Patients with psychiatric or neurological disorders impairing cooperation