The Asia-Pacific Mitral & Tricuspid Valve-in-Valve/Valve-in-Ring Registry (AP ViV Registry)

Launched by NATIONAL HEART CENTRE SINGAPORE · Jul 1, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a special heart procedure called valve-in-valve or valve-in-ring, which is used to treat problems with the heart’s mitral or tricuspid valves. These valves help control blood flow through the heart, and sometimes they need repair or replacement. Instead of open-heart surgery, this procedure uses a small valve placed inside the existing valve through a less invasive method. The study is looking at patients in the Asia-Pacific region who have already had or are planning to have this procedure, to better understand its safety and outcomes.

If you are 21 years or older and have had or are scheduled to have this valve-in-valve or valve-in-ring procedure on your mitral or tricuspid valve since January 2023, you might be eligible to join. People with active infections of the heart (called endocarditis) or other serious health issues may not be able to participate. Participants will be followed by their doctors to collect information about how they do after the procedure. This study is currently looking for patients to join, and it aims to help improve care for people with heart valve problems in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age ≥ 21
• • 2. Had at least one documented Mitral valve-in-valve/valve-in-ring procedure done during the period of 1 Jan 2023 to current date. (Retrospective) OR Planned to undergo a Mitral valve-in-valve/valve-in-ring procedure. (Prospective) OR Had at least one documented Tricuspid valve-in-valve/valve-in-ring procedure done during the period of 1 Jan 2023 to current date. (Retrospective) OR Planned to undergo a Tricuspid valve-in-valve/valve-in-ring procedure. (Prospective)
• Exclusion Criteria:
• • 1. Active endocarditis
• • 2. Any other conditions which investigator deems unsuitable for participation.