The Use of Entropy to Assess Sleep Disordered Breathing in Chronic Respiratory Disease

Launched by UNIVERSITY COLLEGE, LONDON · Jul 8, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how sleep problems affect people with long-term lung diseases like asthma, COPD, bronchiectasis, and others. Many of these patients may have a condition called sleep-disordered breathing, where breathing stops or becomes very shallow during sleep, leading to low oxygen levels. The study aims to use a new method to better understand these breathing issues by analyzing data from sleep tests in more detail. This could help doctors learn why some people with lung diseases have worse sleep-related breathing problems than others.

Adults aged 18 and older who have a chronic lung condition, whether or not they have sleep-disordered breathing, can join the study. People who have had previous sleep tests that showed no problems can also take part as a comparison group. Participants will be asked to sleep while wearing portable monitoring devices that track their breathing and oxygen levels, similar to a home sleep study. The study is currently recruiting volunteers and is open to all genders. If you decide to join, you’ll need to understand the study and agree to it by signing a consent form. This research could help improve how sleep problems in lung diseases are diagnosed and treated in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • All adult patients (≥ 18years) with chronic respiratory disease with/without SDB.
• • patients who have had previously negative studies as a control group.
• • Subject is able to read, understand, and sign the informed consent form.
• • Willing to sleep with portable monitoring devices.
• Exclusion Criteria:
• • Patients who are under 18 years of age at the time of the index study.
• • Contraindications to the use of portable monitoring.
• • Inability to give informed consent to take part in the study.