The Use of Entropy to Assess Sleep Disordered Breathing in Chronic Respiratory Disease
Launched by UNIVERSITY COLLEGE, LONDON · Jul 8, 2025
Trial Information
Current as of July 24, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how sleep problems affect people with long-term lung diseases like asthma, COPD, bronchiectasis, and others. Many of these patients may have a condition called sleep-disordered breathing, where breathing stops or becomes very shallow during sleep, leading to low oxygen levels. The study aims to use a new method to better understand these breathing issues by analyzing data from sleep tests in more detail. This could help doctors learn why some people with lung diseases have worse sleep-related breathing problems than others.
Adults aged 18 and older who have a chronic lung condition, whether or not they have sleep-disordered breathing, can join the study. People who have had previous sleep tests that showed no problems can also take part as a comparison group. Participants will be asked to sleep while wearing portable monitoring devices that track their breathing and oxygen levels, similar to a home sleep study. The study is currently recruiting volunteers and is open to all genders. If you decide to join, you’ll need to understand the study and agree to it by signing a consent form. This research could help improve how sleep problems in lung diseases are diagnosed and treated in the future.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • All adult patients (≥ 18years) with chronic respiratory disease with/without SDB.
- • patients who have had previously negative studies as a control group.
- • Subject is able to read, understand, and sign the informed consent form.
- • Willing to sleep with portable monitoring devices.
- Exclusion Criteria:
- • Patients who are under 18 years of age at the time of the index study.
- • Contraindications to the use of portable monitoring.
- • Inability to give informed consent to take part in the study.
About University College, London
University College London (UCL) is a leading global research institution renowned for its commitment to advancing healthcare through innovative clinical trials. As a prominent sponsor of clinical research, UCL leverages its multidisciplinary expertise and state-of-the-art facilities to conduct rigorous investigations aimed at improving patient outcomes and addressing pressing medical challenges. The institution fosters collaboration among researchers, healthcare professionals, and industry partners, ensuring that its trials adhere to the highest ethical standards and regulatory guidelines. UCL's dedication to translating scientific discoveries into practical applications underscores its role as a vital contributor to the advancement of medical science and public health.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
London, , United Kingdom
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported