The Effect of Dexamethasone Administration Route in Pediatric Brachial Plexus Block

Launched by POZNAN UNIVERSITY OF MEDICAL SCIENCES · Jul 8, 2025

Keywords

ClinConnect Summary

This study is looking at how the way a medicine called dexamethasone is given affects pain and inflammation after arm surgery in children. Dexamethasone is often used to help reduce pain and swelling, and the researchers want to see if giving it through a vein (intravenous) or directly near the nerves in the arm (perineural) works better to control pain after surgery. They will measure how much pain children feel at different times after the operation, along with checking certain blood markers that show inflammation. They will also track how much pain medicine children need after surgery and how quickly they need extra pain relief.

Children who are having surgery on their arm, wrist, or hand, and weigh more than 5 kilograms (about 11 pounds), may be able to join the study. Kids with infections near the surgery site, bleeding problems, weak immune systems, very serious health issues, or who regularly take steroid medicines won’t be eligible. If children take part, they can expect careful monitoring of their pain and recovery after surgery, with the goal of finding the best way to manage pain safely and effectively during and after arm surgery. This research may help improve pain relief for kids having similar surgeries in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • children scheduled for arm/wrist/hand surgery
• • body weight \> 5kg
• Exclusion Criteria:
• • infection at the site of the regional block,
• • coagulation disorders,
• • immunodeficiency,
• • American Society of Anesthesiologists (ASA) physical status of IV or higher,
• • history of regular steroid medication.