Lymphatic Drainage Massage and Melatonin in Post-Orthognathic Surgery Pain and Edema
Launched by BEZMIALEM VAKIF UNIVERSITY · Jul 10, 2025
Trial Information
Current as of July 24, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
Melatonin, a hormone produced by the pineal gland, is a neurochemical substance that functions in harmony with the body's natural rhythm. In addition to its presence in the brain, melatonin can also be found in the retina, bone marrow, intestines, skin, and various blood cells. Conditions such as insomnia or jet lag may benefit from melatonin supplements. Beyond its role in improving sleep quality, melatonin also contributes to regulating the immune system, body temperature, blood pressure, and cortisol hormone levels.
Another important function of melatonin is its powerful free radical-sc...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Patients with dentofacial deformities who are planned to undergo orthognathic surgery
- • 2. Patients who have not previously undergone orthognathic surgery
- • 3. Patients with no systemic diseases
- Exclusion Criteria:
- • 1. Presence of systemic diseases affecting general health
- • 2. Presence of malignant disease in the head and neck region
- • 3. Patients who have previously undergone orthognathic surgery
- • 4. Patients with any bleeding disorders
- • 5. Patients with cardiovascular disease who are under anticoagulant or antiplatelet therapy
About Bezmialem Vakif University
Bezmialem Vakif University is a prominent academic institution based in Istanbul, Turkey, dedicated to advancing medical research and education. As a clinical trial sponsor, the university leverages its state-of-the-art facilities and a multidisciplinary team of experts to conduct innovative research that aims to improve patient outcomes and enhance therapeutic strategies. Bezmialem Vakif University is committed to adhering to rigorous ethical standards and regulatory guidelines, ensuring the integrity and reliability of its clinical trials while fostering collaboration with global research communities. Through its initiatives, the university seeks to contribute significantly to the field of medicine and public health.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Istanbul, Fatih, Turkey
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported