Non-Helium Magnetoencephalography in Autism Spectrum Disorder

Launched by GUANGZHOU WOMEN AND CHILDREN'S MEDICAL CENTER · Jul 3, 2025

Keywords

ClinConnect Summary

This clinical study is looking at how brain activity in boys with Autism Spectrum Disorder (ASD) may be different from that of typically developing children. Researchers are using a special brain scan called magnetoencephalography (MEG), which measures the magnetic signals produced by brain activity. The goal is to see if these brain signals show unique patterns in children with ASD and if MEG could help improve early diagnosis of autism.

Boys between the ages of 6 and 12 who have been diagnosed with ASD and have an IQ above 70 may be eligible to join the study. Participants will have an MEG scan while resting and while doing simple tasks. The scan is painless and non-invasive, meaning it doesn’t involve any injections or surgery. The study is currently recruiting, and it’s important that participants are able to follow instructions during the scan. Children with other neurological conditions, metal implants, or who are taking certain medications may not be able to participate. This research could help doctors better understand autism and develop new tools for earlier and more accurate diagnosis.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Boys aged 6 to 12 years;
• • Diagnosis of Autism Spectrum Disorder meeting DSM-5 criteria;
• • Intelligence quotient (IQ) score \> 70 (assessed via Wechsler Intelligence Scale for Children or other validated cognitive test);
• • Sufficient compliance to participate in MEG experiments.
• Exclusion Criteria:
• • Comorbid neurological disorders, genetic syndromes, or severe developmental disabilities;
• • Metallic implants that may interfere with MEG signal acquisition;
• • Current use of antipsychotic medications or sedatives.