Argon Plasma Treatment for Ovarian Endometrioma Compared to Standard Cystectomy

Launched by ERBE ELEKTROMEDIZIN GMBH · Jul 14, 2025

Keywords

ClinConnect Summary

This clinical trial is studying two different surgical treatments for ovarian endometrioma, which is a type of cyst caused by endometriosis on the ovaries. The goal is to see how each treatment affects the ovarian reserve, meaning how well the ovaries can function afterward. To do this, doctors will compare levels of a hormone called AMH, which helps indicate ovarian health, before and after surgery.

Women who have symptoms that require surgery for ovarian endometrioma and are able to give informed consent may be eligible to participate. The study will include 72 women, who will be randomly assigned to receive either the standard surgery (called cystectomy) or a newer treatment using argon plasma coagulation (APC). After the surgery, participants will have follow-up visits at 3, 6, and 12 months, where their hormone levels will be checked and their recovery monitored. The last visit will be done over the phone. This study is still not recruiting yet, and it excludes women who have had previous ovarian surgeries, recurrent endometriomas, are pregnant or breastfeeding, or are involved in other studies that might affect hormone levels.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Indication for surgical endometrioma treatment according to patient symptoms
• • Signed informed consent
• Exclusion Criteria:
• • Expected lack of patient compliance or inability of the patient to understand the purpose of the clinical trial
• • Prior procedures at the ovaries
• • Recurrent endometrioma (patients with recurrent endometriosis outside of the ovar, e.g. peritoneal endometriosis lesions can be included)
• • Pregnant or breastfeeding patients
• • Participation in any other clinical study that could affect the AMH level or pregnancy