Microscopic Varicocele Bypass Versus Ligation

Launched by KE DOU · Jul 3, 2025

Keywords

ClinConnect Summary

This clinical trial is studying two different types of surgery to treat varicocele, which is a condition where veins in the scrotum become enlarged and can affect fertility. The study compares a newer, detailed surgery called microscopic varicocele transposition with a more common procedure called simple ligation. The goal is to see which surgery is safer and more effective by looking at recovery, sperm quality, complications, and overall patient well-being after surgery.

Men between 18 and 60 years old who have varicocele causing abnormal sperm test results and need surgery may be eligible to join. Participants will be randomly assigned to one of the two surgeries and closely monitored before and after the procedure. This includes ultrasound exams and sperm tests at 1, 3, and 6 months after surgery, as well as checks on hormone levels, pain, and quality of life. The study aims to help doctors choose the best surgical option for patients with varicocele and improve treatment outcomes. All participants will give informed consent and the study follows strict ethical guidelines to ensure safety.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Patients with varicocele and meet the surgical indications
• • Male patients aged between 18 and 60 years old
• • Patients have the willingness to receive treatment, voluntarily participate in this study and sign the informed consent form
• • Semen analysis reveals abnormalities associated with varicocele
• • The patient has no severe dysfunction of vital organs and can tolerate surgery
• • The patient has received no relevant treatment affecting varicocele or semen quality in the past three months
• Exclusion Criteria:
• • Secondary varicocele
• • Complicated with other severe reproductive system diseases
• • Suffering from severe systemic diseases, which may affect the surgical effect or prognosis
• • Presence of coagulation dysfunction or taking medications that affect coagulation function
• • Having a history of allergy to the drugs used in the surgery
• • Having mental illness or cognitive impairment and being unable to cooperate to complete this study
• • Having already participated in other relevant clinical trials.