Artificial Intelligence-assisted Colonoscopy in the Detection and Characterization of Colorectal Lesions

Launched by INSTITUTO DO CANCER DO ESTADO DE SÃO PAULO · Jul 4, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how well artificial intelligence (AI) can help doctors find and understand growths in the colon during a colonoscopy. A colonoscopy is a test where a doctor uses a small camera to look inside the large intestine to check for abnormal growths, which can sometimes lead to colorectal cancer. The study wants to see if using AI during this procedure helps doctors spot more of these growths and better identify which ones might be risky, compared to the usual way of doing a colonoscopy.

People who are 18 years or older and scheduled for a planned colonoscopy may be able to join the study, as long as they agree to participate. However, individuals with certain health issues, like inflammatory bowel disease, a history of colon cancer or surgery, or those who need emergency colonoscopies, cannot join. Participants will undergo a colonoscopy as usual, but with the added help of AI technology during the procedure. The goal is to improve early detection and treatment of potentially harmful colon growths. If you’re considering this trial, it’s important to discuss it with your doctor to see if it’s right for you.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • All patients aged 18 years or older, with an elective indication for colonoscopy who sign the informed consent form agreeing to participate in the study.
• Exclusion Criteria:
• • History of inflammatory bowel disease.
• • History of colorectal cancer.
• • Personal history of colorectal surgery.
• • Contraindication to endoscopic biopsies.
• • History of intestinal polyposis syndromes.
• • Urgent or emergency cases.
• • Presence of severe, decompensated comorbidities, or with a score of 3 or higher according to the American Society of Anesthesiologists (ASA) classification.
• • Incomplete colonoscopy that does not reach the cecum.
• • Insufficient or inadequate bowel preparation, with a score lower than 6 on the Boston Bowel Preparation Scale.
• • Patients who do not agree to participate in the study and do not sign the informed consent form (ICF).