Serial Blood Count Study

Launched by UNIVERSITY OF WASHINGTON · Jul 3, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new way to monitor white blood cells, which are important cells that help fight infections. The study focuses on people with types of neutropenia, a condition where these infection-fighting cells are too low. Researchers want to see how well a new home device, called Athelas One, can measure white blood cell counts and help doctors diagnose and tell the difference between two types of neutropenia: cyclic neutropenia and severe congenital neutropenia. This device has been approved by the FDA for testing, and the researchers believe it could make diagnosis easier and more convenient by allowing people to check their blood counts at home.

People who might be eligible for this study are those 5 years or older who have been diagnosed with severe chronic neutropenia and have a specific genetic mutation called ELANE. Participants should have access to the internet and a smartphone or cell phone that can download apps, as the device works with an app to collect and share results. Adults need to feel comfortable collecting their own blood samples at home. If you join the study, you’ll use the home device regularly to take blood counts, helping doctors understand your condition better without frequent clinic visits. This study is currently recruiting participants of all genders between 18 and 26 years old.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Confirmed diagnosis of severe chronic neutropenia
• • 5 years of age or older, male or female
• • Known positive ELANE mutation
• • Computer if available
• • Internet access
• • Cell phone / Smart phone that can download / install applications (App)
• • Adults that are comfortable obtaining the samples without medical conditions that would make collection of the sample difficult.
• Exclusion Criteria:
• • Diagnosis of severe chronic neutropenia and negative results for the ELANE mutation
• • Less than 5 years of age
• • No internet access
• • No Cell phone or smart phone that cannot download / install applications (App)
• • Adults that are uncomfortable obtaining the samples or have medical conditions that would make collection of the sample difficult.