Post-Hysterectomy Vaginal Length: Horizontal vs. Vertical Closure
Launched by GAZIOSMANPASA RESEARCH AND EDUCATION HOSPITAL · Jul 15, 2025
Trial Information
Current as of August 23, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying two different ways of closing the top of the vagina (called the vaginal cuff) after a vaginal hysterectomy, which is surgery to remove the uterus. The study looks at whether closing the vaginal cuff horizontally (side to side) or vertically (up and down) helps preserve the length of the vagina better after surgery. Keeping the vaginal length is important because it can affect comfort and quality of life after the operation. The study focuses on women who have a severe form of uterine prolapse, where the uterus has dropped down into the vaginal area, and who are having both a vaginal hysterectomy and a procedure called lateral suspension to support the pelvic area.
Women who might be eligible for this study are those with advanced uterine prolapse (stage 3 or 4) who are scheduled for these specific surgeries. To join, participants must agree to take part and sign a consent form. The trial excludes women who have had other types of pelvic support surgeries, those who had their hysterectomy because of cancer, those who had radiation treatment, and those with very thin or fragile vaginal tissue that makes surgery unsafe. Participants can expect to have their surgery with either horizontal or vertical closure, and doctors will measure their vaginal length after surgery to see which method works best. The study is currently looking for volunteers and aims to improve surgical outcomes and quality of life for women undergoing this procedure.
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Cases with vaginal hysterectomy and lateral suspension surgery due to stage 3-4 uterine prolapse Agree to participate in the study and sign the informed consent form
- Exclusion Criteria:
- • Cases that have previously undergone a different suspension surgery due to descent uteri (vaginal hysterectomy and sacrospinous ligament fixation surgery, vaginal hysterectomy and sacrocolopexy surgery, vaginal hysterectomy and high sacouterin plication surgery) Cases that have undergone vaginal hysterectomy due to malignancy Cases that have undergone radiotherapy due to malignancy (brachytherapy) Patients who are not suitable for surgical intervention due to severe vaginal atrophy.
- • Patients who will not be able to comply with the follow-up process. Not accepting to participate in the study or not signing the informed consent form
About Gaziosmanpasa Research And Education Hospital
Gaziosmanpasa Research and Education Hospital is a leading healthcare institution dedicated to advancing medical research and education. With a commitment to innovative clinical practices, the hospital serves as a hub for clinical trials aimed at improving patient outcomes and enhancing therapeutic options. The institution fosters collaboration among multidisciplinary teams, integrating cutting-edge research with exceptional patient care. By prioritizing ethical standards and regulatory compliance, Gaziosmanpasa Research and Education Hospital is poised to contribute significantly to the field of medical science and the development of new treatment modalities.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Istanbul, , Turkey
Patients applied
Trial Officials
yagmur acıyiyen, md
Principal Investigator
Gaziosmanpasa Training and Research Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported