Management of Dentin Hypersensitivity in Patients With Periodontitis

Launched by TRAKYA UNIVERSITY · Jul 15, 2025

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Eligibility criteria

• Inclusion Criteria:
• • 1. No reported or clinically detected dentin hypersensitivity prior to the initiation of non-surgical periodontal therapy.
• • 2. Presence of at least five teeth with probing pocket depths (PPD) ≥6 mm. 3. Systemically healthy individuals with no history of systemic diseases that may interfere with periodontal outcomes.
• • 4. Absence of deep restorations or visible cracks in the teeth adjacent to those selected for hypersensitivity evaluation.
• • 5. No previous treatment for dentin hypersensitivity and no current use of desensitizing toothpaste or products.
• • 6. Clinical diagnosis of Stage III or IV periodontitis, involving periodontal support loss in more than 30% of teeth.
• • 7. A clinical attachment level (CAL) ≥5 mm and radiographic evidence of bone loss extending to the mid-root level.
• • 8. Age 18 years or older at the time of enrollment
• Exclusion Criteria:
• • 1. Use of antibiotics or analgesic medications at the time of screening or during the course of the study.
• • 2. Pregnancy or breastfeeding. 3. Receipt of periodontal therapy within the preceding 6 months. 4. Smoking history of 10 or more cigarettes per day. 5. Regular use of desensitizing toothpaste or other anti-hypersensitivity agents.
• • 6. Presence of parafunctional oral habits (e.g., bruxism, clenching). 7. Existence of non-carious cervical lesions such as erosion, attrition, or abrasion on study or adjacent teeth.
• • 8. High frequency of acidic dietary intake. 9. Inability to meet hypersensitivity perception thresholds following non-surgical periodontal therapy, defined as a Visual Analog Scale (VAS) score \>4 and Schiff Cold Air Sensitivity Scale score of 2 or 3.
• • 10. Contraindications to the use of Er,Cr:YSGG laser therapy, including but not limited to: known allergies to local or topical anesthetics, presence of cardiac devices (e.g., pacemakers or implantable defibrillators), respiratory disease, bleeding disorders, or immunosuppressive conditions. In such cases, written clearance from a physician is required.
• • 11. Known or suspected allergy to any component of the Gluma Desensitizer, specifically hydroxymethyl methacrylate or glutaraldehyde.