Prospective Evaluation of Probabilistic Predictions of Epileptic Seizure Risk Using the EPIDAY Tool

Launched by ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS · Jul 7, 2025

Keywords

ClinConnect Summary

This clinical trial is exploring a new way to predict when someone with epilepsy might have a seizure. Researchers believe that certain warning signs appear before a seizure starts, and by using a smartphone app combined with computer algorithms, they hope to better anticipate these seizures. This could help people with epilepsy manage their condition more effectively and improve their safety.

To take part, you need to be between 18 and 65 years old and have a type of epilepsy called focal epilepsy, diagnosed for at least 18 months. Your brain scans should show no worsening problems, and you must have had seizures on at least two separate days each month. You also need to be able to use a smartphone app to report your symptoms and seizures. Participants will be asked to use this app regularly to track their experiences. It’s important to note that pregnant or breastfeeding women, people with certain other health conditions, or those who have seizures very frequently (more than 15 days a month) cannot join this study. If eligible, you would help researchers understand how well this app can predict seizures before they happen.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age between 18 and 65
• • Focal epilepsy diagnosed for at least 18 months
• • Brain imaging as part of the etiological work-up for epilepsy showing no progressive cause
• • EEG compatible with the diagnosis of epilepsy within the last 10 years
• • At least 2 non-contiguous days of epileptic seizures per month, according to the patient
• • Ability of the patient to understand and use a mobile application on the personal smartphone
• • Free, informed and signed consent
• • Affiliation with a social security scheme (excluding AME)
• Exclusion Criteria:
• • Suspicion or diagnosis of other types of associated malaise: functional dissociative seizures, syncope or other malaise of non-neurological origin
• • Assessment of seizure frequency deemed unreliable by the investigator (eg. due to cognitive impairment)
• • Inability to describe seizures accurately
• • Presence of more than 15 days with seizures per month
• • Participation in other interventional research or exclusion period not expired
• • Pregnant or breastfeeding woman
• • Patient under guardianship, curatorship, deprived of liberty