Continuous Erector Spinae Block Versus Continuous Edge of Laminar Block on The Quality of Analgesia and Diaphragmatic Excursion in Patients With Multiple Rib Fractures
Launched by TANTA UNIVERSITY · Jul 5, 2025
Trial Information
Current as of July 24, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at two different ways to manage pain for patients who have broken several ribs on one side of their chest due to an injury. The study compares two types of continuous nerve blocks—methods where medicine is delivered near the spine to help reduce pain over time—to see which one provides better pain relief and helps the diaphragm (the muscle that helps you breathe) move more easily. This is important because controlling pain well can improve breathing and overall recovery after multiple rib fractures.
Adults between 21 and 65 years old who have at least three broken ribs on one side and are admitted to the intensive care unit soon after their injury might be eligible to join. Participants should not have serious other health problems, bleeding issues, or infections at the treatment site, among other criteria. Those who take part will receive one of the two nerve block treatments and will be monitored closely to see how well their pain is managed and how their breathing muscle works. This study aims to find the safer and more effective way to help patients feel more comfortable and breathe better after rib injuries.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Aged between 21 and 65 years.
- • Both sexes.
- • With unilateral traumatic multiple fracture ribs (≥ 3), admitted to the surgical intensive care unit within the first day of trauma.
- Exclusion Criteria:
- • Patients' rejection.
- • Body mass index ≥ 35 (kg/m2).
- • Bleeding and Coagulation disorders.
- • Known hypersensitivity to the study drugs.
- • Vertebral deformity.
- • Respiratory, cardiac, renal or hepatic dysfunction.
- • Patients with major trauma involving extra-thoracic structures (e.g., head, spine, pelvis, and abdominal visceral injuries).
- • Mental or cognitive dysfunction,
- • History of chronic analgesic or drug abuse.
- • Local infection at the site of the block.
About Tanta University
Tanta University is a prestigious academic institution located in Egypt, dedicated to advancing medical research and education. As a clinical trial sponsor, Tanta University leverages its extensive resources and expertise to conduct innovative research initiatives aimed at improving health outcomes. The university collaborates with a network of healthcare professionals, researchers, and institutions to facilitate rigorous clinical trials across various medical disciplines. Committed to ethical standards and scientific integrity, Tanta University strives to contribute to the global body of knowledge while fostering the next generation of medical professionals.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Tanta, El Gharbia, Egypt
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported