An International Observational Study of Adults With Acute Infection

Launched by UNIVERSITY OF MINNESOTA · Jul 7, 2025

Keywords

ClinConnect Summary

This clinical trial is an international study looking at adults who are hospitalized with sudden infections, like flu, COVID-19, or other serious infections. The goal is to better understand how these infections affect people, what puts someone at risk, and how doctors can best treat them. By collecting information and samples from patients around the world, researchers hope to learn more about different types of infections and use this knowledge to design better treatments and future studies.

Adults aged 18 and older who are in the hospital or emergency room because of a recent infection (symptoms started within the last 30 days) may be eligible to join. People need to give their permission to participate, or someone else can give permission if they aren’t able to do so themselves. The study does not include people who are currently in prison, those receiving only comfort care at the end of life, or anyone who cannot or does not want to take part in the study procedures. Participants can expect their doctors and the research team to collect information and samples during their hospital stay, but this study does not involve new treatments—it’s focused on learning more about infections to help improve care in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥18 years old
• • Admitted to hospital (or in an emergency department with anticipated hospital admission) for the management of a suspected or confirmed acute infectious disease.
• • Onset of symptoms of an infectious disease within the past 30 days.
• • Informed consent for study participation by the participant or a surrogate decision maker if the participant lacks capacity for consent.
• Exclusion Criteria:
• • Current imprisonment (this does not include quarantine for an infectious disease).
• • Patient undergoing comfort care measures only such that treatment focuses on end- of-life symptom management over prolongation of life.
• • Expected inability or unwillingness to participate in study procedures.
• • In the opinion of the investigator, participation in the study is not in the best interest of the patient.