Prognostic Value of Isolated and Combined Score Aspects in Acute Ischemic Stroke

Launched by CENTRE HOSPITALIER DE GONESSE · Jul 15, 2025

Keywords

ClinConnect Summary

This clinical trial, called TARGET-ASPECT, is studying people who have had a specific kind of stroke called an acute ischemic stroke. This happens when a blood clot blocks blood flow to the brain. The patients in this study are treated with both clot-busting medicine and a procedure to remove the clot. Even with these treatments, about half of patients don’t fully recover. The study wants to find out if looking at certain brain images and scores—alone or combined—can help doctors better predict how well patients will do three months after their stroke, and whether their blood vessels open up successfully.

If you are 18 years or older, had this type of stroke confirmed by brain scans, and received both clot-busting medicine and clot removal, you might be able to join. Participants will be followed for about 90 days to see how they recover. The study involves 152 patients and aims to find simple, reliable tools that doctors can use to make better treatment choices in the future. People with bleeding strokes, poor imaging scans, or those who pass away or cannot be followed up early won’t be included. This study may help improve care and recovery predictions for stroke patients like you or your loved ones.

Gender

ALL

Eligibility criteria

• Inclusion Criteria :
• • Patients aged 18 years or older
• • Confirmed acute ischemic stroke on imaging
• • Treated with both thrombolysis and thrombectomy
• • Clinical follow-up data available at 90 days (mRS score)
• Exclusion Criteria :
• • Primary hemorrhagic stroke
• • Early death or loss to follow-up without evaluation
• • Poor-quality imaging that cannot be analyzed