Muscle Quality and Subcutaneous Adipose Tissue in the Rectus Femoris and Rectus Abdominis Muscles: Ultrasound Evaluation and Functional Correlation in Older Adults

Launched by UNIVERSITY OF SALAMANCA · Jul 7, 2025

Keywords

ClinConnect Summary

This clinical trial is focused on understanding how muscle and fat tissue in certain muscles of older women relate to their physical abilities. Using ultrasound, a painless imaging method, researchers will look at muscle quality and fat just under the skin in women aged 65 and older. The main goal is to see if these ultrasound measurements can help explain how well women can perform everyday movements and activities.

Women who are 65 or older, live in the community, and are already part of a specific health program called PReGe may be eligible to join. The study will not include women who have had recent surgeries, certain implants, muscle or nerve diseases, serious mobility problems, sudden weight loss, or specific abdominal issues. Participants can expect a quick, non-invasive ultrasound exam and some simple tests to assess their physical function. This study may help improve understanding of muscle health in older women, which could lead to better ways to support strength and mobility as people age.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Aged ≥ 65 years and living in the community.
• • Female sex.
• • Enrolled as a participant in PReGe program.
• Exclusion Criteria:
• • Recent surgery (\<6 months) involving the abdomen or lower extremities.
• • Presence of methal prostheses or implants in the thigh or abdoinal region.
• • Diagnosed neuromuscular disease (e.g., myopathies, advanced Parkinson's disease.)
• • Musculoskeletal disorders that impair basic mobility or prevent functional testing.
• • Acute illness or clinical decompensation at the time of assessment.
• • Unintentional weight loss \> 5 kg within the past month (suggestive of cachexia risk).
• • Presence of active abdominal hernias or severe diastasis recti.