Postoperative Pain and Flare-Up Rates in Diabetic Type II Patients Following The Use of Bioceramic Intracanal Medication

Launched by MINIA UNIVERSITY · Jul 16, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how two different types of medications used inside the root canal affect pain and sudden flare-ups after root canal treatment in people with controlled type 2 diabetes. The researchers want to find out if the newer bio-ceramic medication works better than the traditional calcium hydroxide medication in reducing pain and swelling after treatment.

People who might join this study are adults with well-controlled type 2 diabetes who have a single-rooted tooth with a small infection at the tip of the root. To take part, the tooth must be healthy aside from the infection, meaning it has no unusual shape, decay, or previous root canal treatment. During the study, all participants will receive a root canal treatment, then will get either the bio-ceramic or calcium hydroxide medication placed inside the tooth. Afterward, patients will be asked to rate their pain several times over the first week, and they should contact the study team if they experience sudden severe pain or swelling. This study is not yet recruiting participants but aims to help improve pain management for diabetic patients after root canal therapy.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with controlled diabetes mellitus type II.
• * Necrotic single rooted teeth:
• • with periapical lesion ranging (1-2mm) in diameter.
• • with complete root formation.
• • Without calcified root canals.
• • Without root caries.
• • Without external or internal root resorption.
• • Without anatomical abnormalities such as fusion.
• Exclusion Criteria:
• • Pregnant females.
• • Patients with other systemic diseases in combination with diabetes mellitus.
• • Patients under antibiotic or analgesic administration.
• • Patients with facial swelling.
• • Teeth that are not indicated for endodontic treatment: bad oral hygiene, mobile teeth, or recessed teeth.
• • Previously endodontically treated teeth.
• • Teeth with sinus tract.