Using Cardiac MRI to Predict Outcomes in Patients With STEMI

Launched by CHINESE PLA GENERAL HOSPITAL · Jul 9, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how detailed heart scans called cardiac MRI can help predict health outcomes in people who have had a specific type of heart attack known as STEMI. After treatment to open blocked heart arteries, patients will have an MRI scan within a week to look closely at how their heart muscle and chambers are working. Using advanced computer technology, including artificial intelligence, researchers will analyze these images to find patterns that might show who is at higher risk for future heart problems like another heart attack, heart failure, or even death. The goal is to improve how doctors understand each patient’s condition and tailor treatment plans more precisely.

People eligible for this study are adults aged 18 to 80 who have had a STEMI heart attack, received treatment to open their arteries (called PCI), and can safely have an MRI scan within seven days after their procedure. Participants will undergo a non-invasive MRI scan, which is painless and similar to a detailed picture of the heart, and then be followed for up to three years to see how they do over time. There is no new treatment involved—this study only collects and analyzes data from routine care to help improve future heart care. Certain conditions, like having implanted devices that don’t work with MRI or kidney problems, may prevent someone from joining. This research aims to help doctors predict heart health more accurately and personalize care for heart attack survivors.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age between 18 and 80 years
• • Diagnosed with ST-segment elevation myocardial infarction (STEMI), defined as chest pain with ST-segment elevation on ECG and elevated cardiac troponin levels
• • Underwent primary percutaneous coronary intervention (PCI)
• • Able to undergo cardiac magnetic resonance (CMR) imaging within 7 days post-PCI
• • Provided written informed consent
• Exclusion Criteria:
• • Contraindications to CMR (e.g., severe claustrophobia, implanted cardiac defibrillators or non-compatible pacemakers)
• • History of revascularization therapy (PCI or CABG) within the previous 6 months
• • Severe valvular heart disease or known cardiomyopathy
• • Presence of bundle branch block or fascicular block that interferes with image interpretation
• • Known allergy to gadolinium-based contrast agents (for those undergoing contrast-enhanced sequences)
• • Estimated glomerular filtration rate (eGFR) \<30 mL/min/1.73m² (if contrast use is anticipated)
• • Pregnant or breastfeeding women